RetinaDigest

In eyes with silicone oil endotamponade for rhegmatogenous retinal detachment, OCT-measured inner retinal layer integrity—particularly RNFL and GCL+IPL thickness—was the strongest predictor of visual outcomes, outperforming macular edema status and silicone oil duration as prognostic factors.

In a prospective cohort of 265 diabetic eyes, elevated baseline deep capillary plexus geometric perfusion deficit (GPDd) on OCTA independently predicted a 77% higher hazard of DR complications and earlier onset by ~4 months, while FAZ enlargement did not independently predict complications after adjustment for GPDd.

PCV prevalence was similarly elevated in Singaporean and Canadian Asian populations (~42%) compared to Canadian Caucasians (~14%), regardless of geographic location, supporting a predominantly genetic basis for PCV susceptibility. OCT-based diagnostic criteria demonstrated consistent morphological features across ethnicities, validating their use as a reliable non-invasive alternative to ICGA.

In this 2-year prospective cohort study of 205 eyes with pachychoroid subtype, progression to a worse disease level was infrequent (7.3%), and neovascularization occurred exclusively in eyes with shallow, irregular RPE elevation at baseline.

Abstract not available — see full article for details.

The phase 3b/4 SALWEEN trial demonstrated that faricimab 6 mg achieved meaningful visual gains (+8.9 letters) and significant anatomical improvements in treatment-naïve PCV patients through 48 weeks, with over half of patients successfully extended to Q20W dosing intervals.

In 502 eyes with intermediate AMD, quantitative OCT biomarkers—particularly ellipsoid zone integrity metrics and hyperreflective foci count—were strongly associated with 2-year progression to advanced atrophic AMD, with a machine learning predictive model achieving an AUC of 0.85.

Abstract not available — see full article for details.

In children with congenital optic disc excavation, greater excavation depth and non-bowl-shaped morphology on B-scan ultrasonography are independently associated with retinal detachment in both morning glory syndrome (MGS) and peripapillary staphyloma (PS), with MGS demonstrating deeper excavation and worse visual outcomes than PS.

Abstract not available — see full article for details.

Posterior segment imaging findings in ocular syphilis follow reproducible temporal patterns relative to symptom duration, with OCT disc edema and certain retinal abnormalities more prevalent in earlier presentations (≤8 weeks), while RPR titers inversely correlate with symptom duration.

Abstract not available — see full article for details.

Abstract not available — see full article for details.