RetinaDigest

In patients with spontaneously resolved acute CSCR, only 55% achieved 20/20 vision, with older age, poorer baseline VA, absence of serous PED, and bilateral disease predicting suboptimal visual outcomes.

Abstract not available — see full article for details.

Aqueous TGF-β1 levels are significantly elevated in eyes with proliferative vitreoretinopathy (PVR) and demonstrate strong discriminative performance as a biomarker, while ACE elevation appears related to retinal detachment rather than PVR specifically.

In a study of 705 fovea-off rhegmatogenous retinal detachment patients, Müller cell cone loss emerged as the strongest independent risk factor for both secondary macular hole development (OR 4.4) and poor visual outcomes following retinal detachment surgery.

Large retrospective cohort study of 549,094 matched patients found that atopic dermatitis significantly increases the risk of retinal detachment (HR 2.74) and postoperative proliferative vitreoretinopathy (HR 1.45).

Abstract not available — see full article for details.

In youth with type 1 diabetes, diabetic retinopathy was associated with modifiable risk factors including poor glycemic control and hypertension, while higher HbA1c correlated with retinal neural layer thinning even without visible retinopathy.

Inner choroidal fibrosis (ICF) in chronic central serous chorioretinopathy is associated with poor visual outcomes and treatment response, with Type 2 ICF showing worse prognosis than Type 1.

Abstract not available — see full article for details.

Abstract not available — see full article for details.

En face OCT using minimum intensity projection (MIP) demonstrated high sensitivity (0.82) for detecting fluorescein angiography-defined inflammatory retinal vascular changes in uveitis patients, significantly outperforming retinal thickness maps.

This retrospective study of 86 ocular toxoplasmosis patients found that adequate sleep (6-8 hours nightly) significantly reduced recurrence risk, while pregnancy after diagnosis increased risk threefold, with trimethoprim-sulfamethoxazole potentially providing better visual outcomes than pyrimethamine-based therapy.

The 0.19 mg fluocinolone acetonide intravitreal implant achieved complete inflammatory resolution in 92.9% of eyes with immune checkpoint inhibitor-associated uveitis, with significant visual improvement and reduced need for adjunctive therapy.

This narrative review examines how ocular immune privilege mechanisms protect the eye under normal conditions but contribute to disease pathogenesis when disrupted, rather than being completely lost in most ocular conditions.

Abstract not available — see full article for details.

This Egyptian multicenter study of 57 patients with inflammatory choroidal neovascularization found VKH disease as the leading cause (47.4%) and demonstrated significant visual acuity improvement and central subfield thickness reduction following treatment.

In a study of 671 Japanese uveitis patients, 31.6% developed uveitic glaucoma, with highest rates in sarcoidosis (50%) and CMV anterior uveitis (77.8%). Greater IOP fluctuation was associated with faster visual field deterioration.

En face OCT demonstrated high sensitivity (94%) but limited specificity (38%) for detecting structural changes associated with fluorescein angiography-defined inflammatory retinal vascular activity in uveitis patients.

Advanced multimodal imaging reveals distinct pathophysiological mechanisms among conditions traditionally grouped as 'white dot syndromes,' challenging the validity of this umbrella classification and supporting disease-specific terminology.

In 4000 patients with posterior uveal melanoma treated with plaque radiotherapy, 82% experienced ≥15-letter vision loss by 10 years, with tumor thickness, proximity to foveola, radiation dose, and diabetes being key predictive factors.

Abstract not available — see full article for details.

An outbreak of 6 cases of postoperative fungal endophthalmitis caused by Sarocladium kiliense following cataract surgery was traced to contaminated trypan blue solution used off-label during the procedures.

Culture-proven endophthalmitis following Boston Type I keratoprosthesis is a rare but devastating complication with poor visual outcomes, despite prompt vitrectomy treatment.