RetinaDigest

Epiretinal proliferation embedding without internal limiting membrane peeling achieved 100% lamellar macular hole closure with significant visual improvement and no major complications in 15 patients.

Volume-rendered swept-source OCT reveals that macular posterior vitreous detachment commonly involves circumferential cortical tearing (89.6% of cases) rather than simple vitreomacular separation, with shallow insertion angles favoring cortical rupture over adhesive failure.

Abstract not available — see full article for details.

In this large registry study of 1,390 pediatric eyes with macular holes, surgical repair achieved greater and faster visual improvement than observation, but both approaches showed clinically significant improvement with low complication rates.

In this retrospective study of 174 patients, new-onset microscotoma occurred in 17.8% of eyes following ERM removal with ILM peeling, with glaucoma, secondary ERM, ICG usage, and male sex identified as significant risk factors.

Following ILM peeling for macular hole surgery, retinal displacement continues asymmetrically toward the optic disc for up to one year, with temporal retinal movement showing strong correlation with larger baseline macular hole size.

Non-neoplastic uveitis masquerade syndromes (NNUMS) frequently mimic inflammatory uveitis, leading to misdiagnosis and unnecessary anti-inflammatory treatment in over half of patients, with multimodal imaging proving crucial for accurate diagnosis.

Management of newly diagnosed proliferative diabetic retinopathy has shifted dramatically from 100% panretinal photocoagulation monotherapy in 2005 to predominantly combination therapy (42.4%) and anti-VEGF monotherapy (36.1%) by 2024.

Over half (54.1%) of PDR patients were lost to follow-up after pars plana vitrectomy, with specific systemic and procedural factors significantly influencing adherence to postoperative care.

Mediterranean diet adherence is consistently associated with slower AMD progression across all disease stages, with complementary benefits to AREDS2 supplementation for intermediate and advanced AMD.

Abstract not available — see full article for details.

Abstract not available — see full article for details.

This retrospective case series of three SSPE patients demonstrates heterogeneous posterior segment involvement that may precede neurological manifestations, with OCT revealing characteristic moth-eaten intraretinal degeneration patterns.

Immune recovery uveitis (IRU) develops in approximately 20% of post-HSCT patients with CMV retinitis, with posterior pole involvement, larger lesion areas, and shorter HSCT-to-CMV intervals being key risk factors.

This systematic review and meta-analysis of 27 European studies (30,471 patients) found anterior uveitis is the most common anatomical subtype (52.1%) in tertiary centers, with non-infectious etiologies predominating (44.9%), though substantial heterogeneity exists across centers.

Pars plana vitrectomy in uveitis patients showed significant visual improvement (63% gained ≥0.3 LogMAR at 6 months) and effective inflammatory control (96.2% clear vitreous at 1 month) when performed for structural complications or diagnostic purposes.

Abstract not available — see full article for details.

A 20-year-old male with tuberculous peritonitis developed choroidal tuberculoma and exudative retinal detachment during anti-tuberculous therapy, demonstrating that ocular tuberculosis can manifest despite appropriate systemic treatment.

Three patients developed culture-negative hypertensive anterior uveitis 2-5 weeks after intravitreal faricimab injections, which resolved within 3 months after discontinuing faricimab and initiating corticosteroid treatment.

This retrospective study of 115,367 intravitreal injections at Bascom Palmer Eye Institute found endophthalmitis rates remained stable at 0.0087% overall, with no significant differences between anti-VEGF agents and generally poor visual outcomes despite treatment.

This IRIS Registry analysis of over 17 million ophthalmic procedures found variable endophthalmitis rates, with open globe repair having the highest incidence (0.94% in adults) and pediatric patients showing significantly higher infection rates after cataract surgery compared to adults.