RetinaDigest

Weekly curated literature from top retina and ophthalmology journals

21 articles
8 categories
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Retinal Detachment & Trauma2 articles

RRD, TRD, giant tears, PVR, ocular trauma, macular hole, ERM

Phacovitrectomy versus vitrectomy for primary rhegmatogenous retinal detachment in phakic eyes: a multicentre propensity-matched study.

Gough … Steel
Ophthalmol RetinaMar 20, 2026

For primary rhegmatogenous retinal detachment (RRD) in phakic eyes, phacovitrectomy provides anatomical outcomes comparable to vitrectomy alone, with any observed visual advantage largely attributable to lens removal rather than a superior retinal treatment effect.

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Patient and Surgeon Disparities in Retinal Detachment Repair Surgery in the Medicare Population from 2011-2021.

Zafar … Woreta
RetinaMar 16, 2026

A retrospective study in the Medicare population (2011-2021) revealed a decline in scleral buckle use, specific patient risk factors for complex RD, and significant geographic and gender disparities among retinal surgeons and patient access to care.

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Diabetic Eye Disease1 article

Diabetic retinopathy surgery, DME treatment, tractional complications

Swept-Source OCT Angiography Vascular Metrics as Biomarkers for Renal Function in Patients with Diabetes Mellitus.

Garg … Miller
Am J OphthalmolMar 17, 2026

Swept-source OCTA non-perfusion area (NPA) is associated with diabetic nephropathy (DN) and its severity, potentially serving as a non-invasive ophthalmic biomarker for renal function in patients with diabetes.

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AMD & Macular Degeneration4 articles

Neovascular AMD, geographic atrophy, submacular hemorrhage

Prevalence and Health Care Disparities of Retinal Conditions: A Meta-Analysis.

Liu … Brodie
JAMA OphthalmolMar 19, 2026

A meta-analysis revealed substantial US prevalence of AMD, DR, DME, and RVO in 2022, with significant disparities by gender, race/ethnicity, and region, highlighting a considerable healthcare burden.

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PULSAR: Clinical Outcomes of Aflibercept 8 mg with Extended Dosing and 2 mg in nAMD in Subgroups Defined by Baseline Characteristics.

Gale …
Ophthalmol RetinaMar 18, 2026

Aflibercept 8 mg achieved visual and anatomic outcomes comparable to aflibercept 2 mg with extended dosing intervals in treatment-naïve nAMD, regardless of baseline disease severity.

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Response to Faricimab in refractory Caucasian Polypoidal Choroidal Vasculopathy (PCV) switchers.

Caruso … De Salvo
RetinaMar 16, 2026

Switching refractory Caucasian PCV patients to faricimab resulted in anatomical and functional stability in the majority, with good tolerability and potential for injection interval extension.

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Retromode Scanning Laser Ophthalmoscopy: A Superior Structural Modality for Visualizing Non-exudative Macular Neovascularization.

Hande & Venkatesh
RetinaMar 16, 2026

Abstract not available — see full article for details.

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Vascular Occlusions4 articles

CRVO, BRVO, retinal ischemia, macular edema from RVO

Stroke Risk After Ischemic Ocular Events: A Real-World Study of an Electronic Health Record Database.

Vought … Iyer
Ophthalmol RetinaMar 20, 2026

Patients experiencing acute ischemic ocular events (IOEs) like retinal artery occlusion or amaurosis fugax are at significant risk for subsequent ischemic stroke (IS) or transient ischemic attack (TIA), with older age, hypertension, cardiovascular disease, and carotid artery stenosis being key risk factors.

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Retinal Astrocytic Hamartoma Complicated by a Branch Retinal Vein Occlusion with Secondary Preretinal Neovascularization.

Errogui … Mrejen
Ophthalmol RetinaMar 18, 2026

Abstract not available — see full article for details.

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Hyperreflective Retinal Nerve Fiber Layer Lesion with Neovascularization.

Akada … Muraoka
Ophthalmol RetinaMar 18, 2026

Abstract not available — see full article for details.

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Reperfusion of Retinal Arteriolar Occlusion After Initiation of Immunosuppressive Therapy in Pediatric Susac Syndrome.

AlHazzani … Abu ElAsrar
Ocul Immunol InflammMar 17, 2026

Early and aggressive immunosuppressive therapy can achieve complete reperfusion of occluded retinal arterioles in pediatric Susac syndrome, even when the full clinical triad is absent.

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Inherited Retinal Disease1 article

IRDs, gene therapy, retinitis pigmentosa, LCA, Stargardt

Double Annulus in SPATA7 Rod Cone Dystrophy.

Sharma … Katoch
Ophthalmol RetinaMar 16, 2026

Abstract not available — see full article for details.

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Pediatric Retina1 article

ROP, FEVR, Coats disease, retinoblastoma, pediatric vitreoretinal

Short-Term Axial Length Changes Predict Progression of Myopic Maculopathy in Pediatric High Myopia.

Jiang … Li
Am J OphthalmolMar 21, 2026

In pediatric high myopes, 2-year axial length (AL) changes, combined with baseline AL, accurately predict long-term myopic maculopathy (MM) progression, with an optimal AL change rate cutoff of 0.325 mm/year.

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Posterior Uveitis7 articles

Posterior uveitis, panuveitis, chorioretinitis, CMV retinitis, ocular inflammation

Ciliochoroidal and Conjunctival Rosai-Dorfman Disease.

Zhou … Wei
OphthalmologyMar 21, 2026

Abstract not available — see full article for details.

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Imaging Measures for the Assessment of Disease Activity in Non-Infectious Posterior Uveitis - Multimodal Imaging in Uveitis (MUV) Taskforce: Report 10.

Agarwal …
Am J OphthalmolMar 18, 2026

A multinational task force developed standardized imaging measures using multimodal imaging to assess disease activity (active, inactive, or equivocal) in non-infectious posterior uveitis (NIPU).

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NON-INFECTIOUS POSTERIOR UVEITIDES - Atypicals, Variants, and Masquerades: the jungle of differential diagnosis.

Bianco … Miserocchi
Am J OphthalmolMar 18, 2026

Non-infectious posterior and panuveitides (NIPUs) comprise a heterogeneous group of inflammatory disorders of the outer retina and choroid, historically referred to as "white dot syndromes." Recent consensus efforts by the Multimodal Imaging in Uveitis (MUV) Task Force have established standardized

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Long-Term Efficacy and Safety of Adalimumab in Pediatric Non-Infectious Uveitis: Including Weekly Dosing Escalation in Refractory Cases.

Esenkaya … Süllü
Ocul Immunol InflammMar 18, 2026

Adalimumab effectively treats pediatric non-infectious uveitis (NIU), and escalating to weekly dosing significantly improves inflammation control and reduces relapse risk in refractory cases without compromising safety.

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The Multimodal Imaging in Uveitis Virtual Special Issue.

Davis
Am J OphthalmolMar 17, 2026

Abstract not available — see full article for details.

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Association of Low Vitamin D with Infectious and Non-Infectious Inflammatory Ocular Disease.

Davoudi … Ness
Ocul Immunol InflammMar 17, 2026

Low serum vitamin D levels are significantly associated with an increased risk of both infectious and non-infectious ocular inflammation, including specific subtypes relevant to retina specialists.

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Long-term follow-up of PLACE and SPECTRA trials: outcomes after successful and unsuccessful half-dose photodynamic therapy for chronic central serous chorioretinopathy.

van den Tillaart … van Dijk
Am J OphthalmolMar 16, 2026

Patients with chronic central serous chorioretinopathy (cCSC) who achieved initial success with half-dose photodynamic therapy (PDT) showed superior long-term visual and anatomical outcomes compared to those with unsuccessful initial treatment. Notably, visual acuity stabilized in both groups after the first follow-up visit.

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Complications & Safety1 article

Endophthalmitis, surgical complications, drug safety, adverse events

The Next Frontier for Transparency in Cancer Randomized Clinical Trials-Data and Safety Monitoring Boards.

Trinquart & Dizon
JAMA OncolMar 19, 2026

Abstract not available — see full article for details.

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