RetinaDigest

This case report describes Schwartz-Matsuo syndrome in a 38-year-old male with chronic rhegmatogenous retinal detachment, highlighting outer retinal corrugations on OCT as a novel diagnostic biomarker for this challenging condition.

Abstract not available — see full article for details.

Retinal detachment occurs in 1.32% of eyes following penetrating keratoplasty, typically presenting with severe anterior proliferative vitreoretinopathy that creates a unique traction pattern without identifiable retinal breaks.

A systematic review of 174 economic evaluation studies in retinal disease found poor reporting quality with only 63% compliance to CHEERS guidelines, particularly lacking in stakeholder engagement, distributional effects, and model transparency.

Aflibercept monotherapy achieved absence of diabetic macular edema 14.6 weeks sooner and very good vision 12 weeks sooner compared to bevacizumab-first treatment, though overall success rates were similar between approaches.

PDT remains clinically effective for chronic central serous retinopathy but faces significant reimbursement barriers in the US, leading to underutilization and avoidable vision loss despite being the most effective treatment for this condition.

This cross-sectional study of 353 Asian patients with neovascular AMD found reticular pseudodrusen (RPD) in 14.4% of patients, which is lower than reported Western populations, but RPD remained strongly associated with thin choroid and type 3 macular neovascularization regardless of ethnicity.

This systematic review and meta-analysis of 1,096 eyes with extensive macular atrophy with pseudodrusen (EMAP) reveals a distinct retinal phenotype affecting middle-aged patients with poor visual outcomes, showing mean visual acuity loss of 3 lines over 2 years and strong association with rheumatic fever in Brazilian populations.

Abstract not available — see full article for details.

Among 74 patients with syphilitic uveitis, 37% developed chronic inflammation, with cystoid macular edema and longer symptom duration before treatment identified as significant risk factors for chronicity.

Abstract not available — see full article for details.

Three patients with acute retinal pigment epithelitis (ARPE) unresponsive to systemic steroids showed significant visual improvement and outer retinal layer regeneration after treatment with oral valacyclovir.

This retrospective Brazilian study of 20 patients demonstrates that diagnostic pars plana vitrectomy with strategic laboratory testing effectively identifies intraocular malignancies and infectious etiologies in uveitis cases, with intraocular lymphoma confirmed in 8 patients using cytology, flow cytometry, and IL-10/IL-6 ratios.

In uveitis patients with tattoos, intermittent tattoo swelling was reported in 28.1% and was associated with sarcoidosis in 34.9% of these cases, suggesting tattoo swelling is a useful clinical indicator for sarcoidosis screening.

This case series of seven pediatric VKH patients (ages 3-17) demonstrates that cataract and glaucoma are the most common complications, with adalimumab showing promise as an effective adjunctive therapy for refractory cases.

This Colombian multicenter study of 1,716 non-infectious uveitis patients found that 59% had visual impairment and 30% were blind, with panuveitis, granulomatous inflammation, and ocular complications being the strongest risk factors for poor visual outcomes.

Abstract not available — see full article for details.

Abstract not available — see full article for details.

This retrospective study of 46 culture-proven Candida endophthalmitis cases found that endogenous infections (predominantly C. albicans) had significantly better visual outcomes than exogenous infections, which were more commonly caused by non-albicans species and associated with recent ocular procedures.